Suzanne A Eccles: search on Z-Library

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1

The Identification of 2-(1 H -Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2- d ]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer †

Folkes, Adrian J., Ahmadi, Khatereh, Alderton, Wendy K., Alix, Sonia, Baker, Stewart J., Box, Gary, Chuckowree, Irina S., Clarke, Paul A., Depledge, Paul, Eccles, Suzanne A., Friedman, Lori S., Hayes,

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 659 KB

english, 2008

2

Tumour-microenvironmental interactions: paths to progression and targets for treatment

Carol Box, Susanne J. Rogers, Marta Mendiola, Suzanne A. Eccles

Journal:

Seminars in Cancer Biology

Year:

2010

Language:

english

File:

PDF, 746 KB

english, 2010

3

Effects of anti-proliferative lichen metabolite, protolichesterinic acid on fatty acid synthase, cell signalling and drug response in breast cancer cells

Bessadóttir, Margrét, Skúladóttir, Edda Á., Gowan, Sharon, Eccles, Suzanne, Ómarsdóttir, Sesselja, Ögmundsdóttir, Helga M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

4

Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling

Wilkie, Scott, Schalkwyk, May C. I., Hobbs, Steve, Davies, David M., Stegen, Sjoukje J. C., Pereira, Ana C. Parente, Burbridge, Sophie E., Box, Carol, Eccles, Suzanne A., Maher, John

Journal:

Journal of Clinical Immunology

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

5

Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis

Pornchai O-charoenrat, Peter Rhys-Evans, Suzanne A. Eccles

Journal:

Year:

2001

Language:

english

File:

PDF, 347 KB

english, 2001

6

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models

Udai Banerji, Nivedita Sain, Swee Y. Sharp, Melanie Valenti, Yasmin Asad, Ruth Ruddle, Florence Raynaud, Michael Walton, Suzanne A. Eccles, Ian Judson, Ann L. Jackman, Paul Workman

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 365 KB

english, 2008

7

Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands

Pornchai O-charoenrat, Peter Rhys-Evans, William J. Court, Gary M. Box, Suzanne A. Eccles

Journal:

Clinical and Experimental Metastasis

Year:

1999

Language:

english

File:

PDF, 294 KB

english, 1999

8

THE SIGNIFICANCE OF MACROPHAGES IN HUMAN AND EXPERIMENTAL TUMORS

Peter Alexander, Suzanne A. Eccles, C. L. L. Gauci

Journal:

Annals of the New York Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 481 KB

english, 1976

9

Signaling pathways required for matrix metalloproteinase-9 induction by betacellulin in head-and-neck squamous carcinoma cells

Pornchai O-charoenrat, Adisak Wongkajornsilp, Peter H. Rhys-Evans, Suzanne A. Eccles

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 450 KB

english, 2004

10

Bayesian estimation of changes in transverse relaxation rates

Simon Walker-Samuel, Matthew Orton, Lesley D. McPhail, Jessica K. R. Boult, Gary Box, Suzanne A. Eccles, Simon P. Robinson

Journal:

Magnetic Resonance in Medicine

Year:

2010

Language:

english

File:

PDF, 537 KB

english, 2010

11

SARCOMA CELLS ENGINEERED TO SECRETE IFN-γ OR IL-2 ACQUIRE SENSITIZATION TO IMMUNE CELL KILLING VIA DIFFERENT MECHANISMS

Claudia L. Flemming, Poulam M. Patel, Gary Box, Suzanne A. Eccles, Mary K.L. Collins

Journal:

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

12

SPIE Proceedings [SPIE SPIE BiOS - San Francisco, California, United States (Saturday 1 February 2014)] Photons Plus Ultrasound: Imaging and Sensing 2014 - Non-invasive molecular profiling of cancer using photoacoustic imaging of functionalized gold nanorods

Oraevsky, Alexander A., Wang, Lihong V., Shah, Anant J., Alles, Erwin J., Box, Carol, Eccles, Suzanne A., Robinson, Simon P., deSouza, Nandita, Bamber, Jeffrey C.

Year:

2014

Language:

english

File:

PDF, 3.71 MB

english, 2014

13

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma

Al-Saffar, Nada M. S., Troy, Helen, Wong Te Fong, Anne-Christine, Paravati, Roberta, Jackson, L. Elizabeth, Gowan, Sharon, Boult, Jessica K. R., Robinson, Simon P., Eccles, Suzanne A., Yap, Timothy A.

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

14

Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases

Zhang, Chi, Stockwell, Simon R., Elbanna, May, Ketteler, Robin, Freeman, Jamie, Al-Lazikani, Bissan, Eccles, Suzanne, De Haven Brandon, Alexis, Raynaud, Florence, Hayes, Angela, Clarke, Paul A., Workm

Journal:

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

15

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall, Lisa Patterson, Miriam Zimmermann, William Court, Cara Lomas, Marta Mendiola, David Hardisson, Suzanne A Eccles

Journal:

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

16

Lymphatic metastasis in breast cancer: importance and new insights into cellular and molecular mechanisms

Suzanne Eccles, Lenaic Paon, Jonathan Sleeman

Journal:

Clinical and Experimental Metastasis

Year:

2007

Language:

english

File:

PDF, 646 KB

english, 2007

17

Preclinical drug development for childhood cancer

Moreno, Lucas, Chesler, Louis, Hargrave, Darren, Eccles, Suzanne A, Pearson, Andrew DJ

Journal:

Expert Opinion on Drug Discovery

Year:

2011

Language:

english

File:

PDF, 479 KB

english, 2011

18

Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI

Boult, Jessica K.R., Box, Gary, Vinci, Maria, Perryman, Lara, Eccles, Suzanne A., Jones, Chris, Robinson, Simon P.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

19

Value of combining dynamic contrast enhanced ultrasound and optoacoustic tomography for hypoxia imaging

Shah, Anant, Bush, Nigel, Box, Gary, Eccles, Suzanne, Bamber, Jeffrey

Journal:

Year:

2017

Language:

english

File:

PDF, 4.19 MB

english, 2017

20

Kurt Hellmann D.M., D.Phil. Oxon. A happy 90th birthday!

Eccles, Suzanne A., Steiner, Rudolf K.

Journal:

Clinical and Experimental Metastasis

Year:

2012

Language:

english

File:

PDF, 181 KB

english, 2012

21

Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library

Welford, Amanda J, Caldwell, John J., Liu, Manjuan, Richards, Meirion, Brown, Nathan, Lomas, Cara, Tizzard, Graham J., Pitak, Mateusz B., Coles, Simon J., Eccles, Suzanne A., Raynaud, Florence I., Col

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

22

MET and RON Receptor Tyrosine Kinases: Novel Therapeutic Targets in Squamous Cell Carcinoma of the Head and Neck

Rogers, Susanne, Box, Carol, Nutting, Christopher, Rhys Evans, Peter, Harrington, Kevin, Eccles, Suzanne

Journal:

Current Enzyme Inhibition

Year:

2007

Language:

english

File:

PDF, 271 KB

english, 2007

23

Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck

Susanne J Rogers, Carol Box, Philip Chambers, Yolanda Barbachano, Christopher M Nutting, Peter Rhŷs-Evans, Paul Workman, Kevin J Harrington, Suzanne A Eccles

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

24

An ineffective monoclonal antibody-ricin A chain conjugate is converted to a tumouricidal agent in vivo by subsequent systemic administration of ricin B chain

Suzanne A. Eccles, Deirdre P. McIntosh, Helen P. Purvies, Alan J. Cumber, Geoffrey D. Parnell, J. Anthony Forrester, Jennifer M. Styles, Christopher J. Dean

Journal:

Cancer Immunology, Immunotherapy

Year:

1987

Language:

english

File:

PDF, 506 KB

english, 1987

25

The identification of novel PLC-γ inhibitors using virtual high throughput screening

Jóhannes Reynisson, William Court, Ciaran O’Neill, James Day, Lisa Patterson, Edward McDonald, Paul Workman, Matilda Katan, Suzanne A. Eccles

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 697 KB

english, 2009

26

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models

Banerji, Udai, Sain, Nivedita, Sharp, Swee Y., Valenti, Melanie, Asad, Yasmin, Ruddle, Ruth, Raynaud, Florence, Walton, Michael, Eccles, Suzanne A., Judson, Ian, Jackman, Ann L., Workman, Paul

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 633 KB

english, 2018

27

Effects of retinoids on growth and dissemination of malignant tumours: Immunological considerations

Suzanne A. Eccles

Journal:

Biochemical Pharmacology

Year:

1985

Language:

english

File:

PDF, 1.09 MB

english, 1985

28

Brk Protects Breast Cancer Cells from Autophagic Cell Death Induced by Loss of Anchorage

Amanda J. Harvey, Caroline J. Pennington, Sarah Porter, Rajpal S. Burmi, Dylan R. Edwards, William Court, Suzanne A. Eccles, Mark R. Crompton

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

29

A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells

Miranda, Elena, Nordgren, Ida K., Male, Abigail L., Lawrence, Charlotte E., Hoakwie, Franciane, Cuda, Francesco, Court, William, Fox, Keith R., Townsend, Paul A., Packham, Graham K., Eccles, Suzanne A

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.73 MB

english, 2013

30

Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion

Pornchai O-Charoenrat, Peter Rhys-Evans, Helmout Modjtahedi, William Court, Gary Box, Suzanne Eccles

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 277 KB

english, 2000

31

Metastasis: recent discoveries and novel treatment strategies

Suzanne A Eccles, Danny R Welch

Journal:

Year:

2007

Language:

english

File:

PDF, 416 KB

english, 2007

32

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3- d ]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Brough, Paul A., Barril, Xavier, Borgognoni, Jenifer, Chene, Patrick, Davies, Nicholas G. M., Davis, Ben, Drysdale, Martin J., Dymock, Brian, Eccles, Suzanne A., Garcia-Echeverria, Carlos, Fromont, Ch

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 4.07 MB

english, 2009

33

Treatment of implanted liver tumors with focused ultrasound

Lili Chen, Gail ter Haar, C.R Hill, Suzanne A Eccles, Gary Box

Journal:

Ultrasound in Medicine & Biology

Year:

1998

Language:

english

File:

PDF, 1.26 MB

english, 1998

34

Editorial introduction

Suzanne Eccles, Tatsuro Irimura, Dan Welch

Journal:

Clinical and Experimental Metastasis

Year:

2009

Language:

english

File:

PDF, 86 KB

english, 2009

35

Breast cancer metastasis: when, where, how?

Suzanne A Eccles, Lenaic Paon

Journal:

Year:

2005

Language:

english

File:

PDF, 37 KB

english, 2005

36

Use of CD44 variant 3 isoforms as a non-invasive investigation for colorectal cancer and adenomatous polyps

Matthew G. Tutton, Mark G. George, Suzanne Eccles, Ian Swift, Muti Abulafi

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 183 KB

english, 2001

37

Neonatal Admission and Its Relationship to Maternal Pain

Cooper, Alannah L., Brown, Janie A., Kelly, Suzanne, Eccles, Siobhan P., Parsons, Richard, Osseiran-Moisson, Rebecca

Journal:

The Journal of Perinatal & Neonatal Nursing

Year:

2020

Language:

english

File:

PDF, 251 KB

english, 2020

38

Inhibition of growth and spontaneous metastasis of syngeneic transplantable tumors by an aromatic retinoic acid analogue

Suzanne A. Eccles, Susan C. Barnett, Peter Alexander

Journal:

Cancer Immunology, Immunotherapy

Year:

1985

Language:

english

File:

PDF, 587 KB

english, 1985

39

Inhibition of growth and metastasis of syngeneic transplantable tumours by an aromatic retinoic acid analogue

Suzanne A. Eccles, Helen P. Purvies, Susan C. Barnett, Peter Alexander

Journal:

Cancer Immunology, Immunotherapy

Year:

1985

Language:

english

File:

PDF, 559 KB

english, 1985

40

10.1038/10455

Eccles, Suzanne A.

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 159 KB

english, 1999

41

The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck

Rogers, Susanne J, Box, Carol, Harrington, Kevin J, Nutting, Chris, Rhys-Evans, Peter, Eccles, Suzanne A

Journal:

Expert Opinion on Therapeutic Targets

Year:

2005

Language:

english

File:

PDF, 661 KB

english, 2005

42

Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells

Amornsupak, Kamolporn, Insawang, Tonkla, Thuwajit, Peti, O-Charoenrat, Pornchai, Eccles, Suzanne A, Thuwajit, Chanitra

Journal:

Year:

2014

Language:

english

File:

PDF, 2.32 MB

english, 2014

43

Three-Dimensional (3D) Tumor Spheroid Invasion Assay

Vinci, Maria, Box, Carol, Eccles, Suzanne A.

Journal:

Journal of Visualized Experiments

Year:

2015

Language:

english

File:

PDF, 61 KB

english, 2015

44

Phosphoinositide 3-Kinase Signalling Pathways in Tumor Progression, Invasion and Angiogenesis

Brader, Sharon, Eccles, Suzanne A

Journal:

Year:

2004

File:

PDF, 1.23 MB

2004

45

Parallels in invasion and angiogenesis provide pivotal points for therapeutic intervention

Eccles, Suzanne A.

Journal:

The International Journal of Developmental Biology

Year:

2004

Language:

english

File:

PDF, 532 KB

english, 2004

46

[Biotechnology Annual Review] Volume 11 || Cell migration/invasion assays and their application in cancer drug discovery

Eccles, Suzanne A.

Year:

2005

Language:

english

File:

PDF, 1.15 MB

english, 2005

47

c-erbB-2 as a target for immunotherapy

Eccles, Suzanne

Journal:

Expert Opinion on Investigational Drugs

Year:

1998

Language:

english

File:

PDF, 197 KB

english, 1998

48

Erratum to: Kurt Hellmann D.M., D.Phil. Oxon. A happy 90th birthday!

Eccles, Suzanne A., Steiner, Rudolf K.

Journal:

Clinical and Experimental Metastasis

Year:

2015

Language:

english

File:

PDF, 293 KB

english, 2015

49

Structure-based optimization of potent, selective and orally bioavailable CDK8 inhibitors discovered by high throughput screening

Czodrowski, Paul, Mallinger, Aurélie, Wienke, Dirk, Esdar, Christina, Poeschke, Oliver, Busch, Michael, Rohdich, Felix, Eccles, Suzanne A., Ortiz Ruiz, Maria Jesus, Schneider, Richard, Raynaud, Floren

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.71 MB

english, 2016

50

The pharmacological audit trail (PhAT): Use of tumor models to address critical issues in the preclinical development of targeted anticancer drugs

Rossanese, Olivia, Eccles, Suzanne, Springer, Caroline, Swain, Amanda, Raynaud, Florence I., Workman, Paul, Kirkin, Vladimir

Journal:

Drug Discovery Today: Disease Models

Year:

2016

Language:

english

File:

PDF, 788 KB

english, 2016

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